How Breast Cancer Can Occur?

How Breast Cancer Can Occur?



     Researchers still don't know exactly what causes breast cancer. Like other cancers, breast cancer is a condition in which certain cells grow abnormally and can not be controlled. Gradually, these cancer cells will attack the nearest healthy breast tissue and eventually spread to the rest of the body.

     Further, the researchers have managed to isolate some of the genes that, if it is demoted, it would seem its contribution to the development of breast cancer. The gene mutation of this gene is cancer 1 (BRCA1) and cancer gene 2 (BRCA2). Both of these genes are found in approximately 10% of people with breast cancer patients. However, even with the presence of a gene mutation, experts are still unable to establish the cause of additional biochemical interactions that are required in the development of breast cancer cells.

    There may be some specific aspects in the medical history or lifestyle you can increase the risk of breast cancer. Below are some of the risk factors of breast cancer. If you have concerns, consult with your doctor.

Risk factors that cannot be avoided

Gender

    Women diagnosed with breast cancer is 100 times more often than men. It is associated with female sex hormones, particularly estrogen and progesterone. In some cases of breast cancer, both these hormones act as a trigger for growth and cell division. The risk of cancer may increase due to breast cells that are often exposed to a second exposure to this hormone during the menstrual cycle.

The age of

     According to the study of the American Cancer Society, more than two-thirds of the cases of breast cancer found in women aged 55 years and over. Only an eighth of the population of women found to have breast cancer at the age of less than 45 years old. Breast cancer in men is a common attack men aged 60-70 years.

Family medical history

     Higher-risk women affected by breast cancer if they have a direct blood relationship with undiagnosed breast cancer, for example, mother, sister, or child. A woman will risk five times more prone to breast cancer if she has two direct relationship with those people with breast cancer.

Genetic

     According to the Memorial Sloan Kettering Cancer Center, BRCA1 and BRCA genetic mutations, so far this is the most common cause of breast cancer is a derivative. The overall incidence of accounting for almost 10% of breast cancer cases lifetimes. BRCA mutation increases the risk against breast cancer until it reaches 85% age 70 years, in some families.

     Researchers suggest that Eastern European lady who has a background of Ashkenazi Jewish tribes reportedly have BRCA mutations is very high, almost outside the normal range. BRCA1 mutation generally will only affect the risk of breast cancer in women, but BRCA2 mutations have a share as a good breast cancer risk factors in women as well as men. Other genes that have a role in breast cancer the derivative is ATM, PTEN, p53, CHEK2, and CDH1.

     European-born woman was judged more susceptible to breast cancer. Even so, African American women have a chance of survival for very small to survive the disease. Breast cancer has also become a major cause of death in Hispanic women.

     In Indonesia, breast cancer in Indonesia was ranked as the first cause of death in women, beating a number of other types of cancer. The incidence of death due to breast cancer in women reach 21.4% based on profile data the cancer mortality (Cancer Mortality Profile) released by the WHO year of 2014.

Personal factors

Some physical characteristics have shown can increase risks to breast cancer, including:

  • Early menstrual period, before 12 years
  • Menopause after 55 years (menopause is delayed)
  • It has big tits

Lifestyle factors

    A certain lifestyle that you tekuni can contribute indirectly towards your chances of contracting breast cancer. According to the American Cancer Society, the lifestyle includes:

  • Obesity or overweight
  • Excessive alcohol consumption
  • Do not have children
  • Having a first child after age 35 years
  • Taking birth control pills
  • Use of hormone replacement therapy

The trigger factors of risk in men

     Although women pertained more prone to breast cancer, did not close the possibility for man to have risk factors. Risk factors that allow, including:

  • High estrogen levels (due to cirrhosis of the liver, for example) or using estrogen drugs (used to treat prostate cancer)
  • Exposed to radiation exposure
  • Older than 60 years
  • Obesity
  • Klinefelter Syndrome (congenital hormone abnormality)
  • A genetic mutation of the derivative (BCRA2)
  • Family medical history related to breast cancer

It is important to keep in mind

      Consult with your doctor about various problems You're worried about risk factors. You may be able to change and adjust Your lifestyle to decrease the chance of knowing your risk of breast cancer. Discuss with your physician regarding your medical and family history to make sure doctors get the right information to diagnose your risk.

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